Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Cryptic Isolates from <i>Aspergillus</i> Section <i>Fumigati</i>

Abstract

The antifungal susceptibility of <i>Aspergillus</i> cryptic species is poorly known. We assessed 51 isolates, belonging to seven <i>Fumigati</i> cryptic species, by the EUCAST reference method and the concentration gradient strip (CGS) method. Species-specific patterns were observed, with high MICs for azole drugs, except for <i>Aspergillus hiratsukae</i> and <i>Aspergillus tsurutae</i>, and high MICs for amphotericin B for <i>Aspergillus lentulus</i> and <i>Aspergillus udagawae</i> Essential and categorical agreements between EUCAST and CGS results were between 53.3 and 93.3%.