Concepedia

The ERα-miR-575-p27 feedback loop regulates tamoxifen sensitivity in ER-positive Breast Cancer

Shu-Shu Liu, Yun Li, Hui Zhang, Di Zhang, Xiaobei Zhang, Xin Wang, Yue Yu

Theranostics · 2020 · 26 citations · 21 references

DOIFull text

Open access

Concepts

Abstract

Our data reveal the ERα-miR-575-CDKN1B feedback loop in ER+ breast cancer, suggesting that miR-575 can be used as a prognostic biomarker in patients with ER+ breast cancer, as well as a predictor or a promising target for tamoxifen sensitivity.

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