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Creation of a robust and R-selective ω-amine transaminase for the asymmetric synthesis of sitagliptin intermediate on a kilogram scale

Kilogram ScaleBioorganic ChemistryBiochemistryNatural SciencesR-selective ω-Amine TransaminaseOrganic ChemistrySynthetic ChemistryPharmacologyPharmaceutical ChemistrySitagliptin IntermediateNatural Product Synthesis