Potential treatment with Chinese and Western medicine targeting NSP14 of SARS-CoV-2

A Novel Coronavirus from Patients with Pneumonia in China, 2019

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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett et al. · Science · 2020 · 9.7K citations · Full text

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

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Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro

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Medicine, Immunology, Antiviral Drug Development +7

Predicting commercially available antiviral drugs that may act on the novel coronavirus (SARS-CoV-2) through a drug-target interaction deep learning model

Bo Ram Beck, Bonggun Shin, Yoonjung Choi et al. · Computational and Structural Biotechnology Journal · 2020 · 780 citations · Full text