Two new homoisoflavones from<i>Portulaca oleracea</i>L. and their activities

Abstract

Two new compounds, identified as 3-(2-hydroxybenzyl)-6,8-dimethoxy-4H-chromen-4-one (<b>1</b>), named oleracone J and 3-(2-hydroxybenzyl)-6,8-dimethoxychroman-4-one (<b>2</b>), named oleracone K, were isolated from <i>Portulaca oleracea</i> L., and the structures of them were determined by spectroscopy, including one-dimensional and two-dimensional nuclear magnetic resonance, high-resolution electrospray ionisation time-of-flight mass spectrometry. The two compounds have scavenging activities in 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical quenching assay, with IC₅₀ values of 18.34, 23.92 μM, and anticholinesterase activities with IC₅₀ values of 59.08, 67.89 μM, respectively.