Swelling Behavior of Cross-link PVA with Glutaraldehyde

Fadhel S. Matty, Maha T. Sultan, Adiba Kh. Amine

SHILAP Revista de lepidopterología · 2015 · 12 citations · 2 references

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Abstract

The polymeric hydrogels composed of poly vinyl alcohol (m.wt 72000) and glutaraldehyde(5%,8% and 10%) , have been thermally prepared for the purpose of studying their swelling and drug release behavior . The swelling ratio was measured for all the hydrogel samples at 37°C, in three different media pH (1.2, 4.7 and 6.8) as a function of time. The results show that the maximum swelling ratios were arranged as follows :pH =6.8 > pH =4.7 > pH =1.2 hydrogels cross linked PVA showed a typical pH responsive behavior such as high pH has maximum swelling while low pH shows minimum swelling.

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