Cochlear Implantation in a Patient with a Novel <i>POU3F4</i> Mutation and Incomplete Partition Type-III Malformation

Abstract

A novel frame shift variant c.400_401insACTC (p.Q136LfsX58) in the <i>POU3F4</i> gene was identified in a Chinese family with X-linked inheritance hearing loss. A patient with this mutation and IP-III malformation could get good benefits from CI. However, the outcomes of the cochlear implantation might decline as the patient grows old.