Theranostics · 2020 · 50 citations · 35 references
MedicineCancer BiologyOncologyMetastasisMolecular OncologyTranscriptional RegulationAngiogenesisAngiogenesis In CancerCancer Cell SignalingCancer TranscriptomicsOncogenic Signaling PathwaysTranscription Factor OncogenesAngiogenic ResponseCancer Cell MigrationCancer Metastasis MechanismsLuciferase Reporter AssaysLuciferase ReportersTranscriptional Dysregulation In CancerZinc Binding ProteinsZinc Finger Transcription Factors
These findings highlight the mechanism by which dysregulation of Kras/YY1/ZNF322/Shh transcriptional axis enhances neo-angiogenesis and cancer progression in lung cancer. Therapeutic strategies that target Kras/YY1/ZNF322A/Shh signaling axis may provide new insight on targeted therapy for lung cancer patients.
35
A Comprehensive Survey of Ras Mutations in Cancer
Ian A. Prior, Paul D. Lewis, Carla Mattos · Cancer Research · 2012 · 2.1K citations · Full text
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
Zoltàn Arany, ShiYin Foo, Yanhong Ma et al. · Nature · 2008 · 1.1K citations · Full text
<i>STAT3</i> Plays a Critical Role in <i>KRAS</i> -Induced Pancreatic Tumorigenesis
Ryan B. Corcoran, Gianmarco Contino, Vikram Deshpande et al. · Cancer Research · 2011 · 414 citations · Full text
Medicine, Cancer Biology, Oncology +17
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
Peter M.K. Westcott, Kyle Halliwill, Minh D. To et al. · Nature · 2014 · 342 citations · Full text