Phase 1 study of concurrent sunitinib and image‐guided radiotherapy followed by maintenance sunitinib for patients with oligometastases

Johnny Kao, Stuart H. Packer, Ha Linh Vu, Myron Schwartz, Max W. Sung, Richard G. Stock, Yeh‐Chi Lo, Delphine Huang, Shu‐Hsia Chen, Jamie A. Cesaretti

Cancer · 2009 · 89 citations · 25 references

Abstract

Addition of SU (25 to 37.5 mg) to IGRT is tolerable in patients with oligometastases, without potentiation of RT toxicity. On the basis of promising antitumor responses observed with this novel combination, a multi-institutional phase 2 trial using SU 37.5 mg/RT 50 Gy is ongoing.

References

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