"Aphrodisiac Activity of Roots of Mimosa pudica Linn. Ethanolic Extract in Mice"

Abstract

The present study was aimed to investigate the effect ethanolic extract of roots of Mimusa pudica Linn. (Mimosae) on libido of sexually normal Swiss Albino male mice. The suspension of the extract was administered orally at the dose of 100, 250, and 500 mg / kg, to different groups of male mice (n = 6) once a day for seven days. The female albino mice involved in mating were made receptive by hormonal treatment. The general libido and potency were determined and compared with the standard reference drug sildenafil citrate. A change in hormonal parameter like testosterone was evaluated. Oral administration of the extract significantly increased the libido and hormonal levels of testosterone. The most appreciable effect of the extract was observed at the dose of 500 mg/kg. The results indicated that the ethanolic extract of roots of Mimusa pudica Linn. (Mimosae) produced a significant and sustained increase in the aphrodisiac activity of normal male mice, without any adverse effects.