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Publication | Open Access

Platelet Dysfunction and Thrombosis in JAK2 <sup>V617F</sup> -Mutated Primary Myelofibrotic Mice

DOIFull Paper Access

45

Citations

23

References

2020

Year

Shinobu Matsuura, Cristal Reyna Thompson, Mostafa Belghasem, Roelof H. Bekendam, Andrew Piasecki, Orly Leiva, Anjana Ray, Joseph E. Italiano, Moua Yang, Glenn Merill-Skoloff,
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Together, our study highlights for the first time the influence of a hyperactive JAK2 on platelet activation-induced ADP secretion and dense granule homeostasis, with consequent effects on platelet activation properties.

References

YearCitations

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