Concepedia

Publication | Open Access

Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity

DOIFull Paper Access

226

Citations

36

References

2020

Year

Barnaby Edward Young, Sean Wei Xiang Ong, Lisa F. P. Ng, Danielle E. Anderson, Wan Ni Chia, Po Ying Chia, Li Wei Ang, Tze Minn Mak, Shirin Kalimuddin, Louis Yi Ann Chai,
Clinical Infectious Diseases

Abstract

We found virus viability was associated with lower PCR Ct value in early illness. A stronger antibody response was associated with disease severity. The overactive proinflammatory immune signatures offer targets for host-directed immunotherapy, which should be evaluated in randomized controlled trials.

References

YearCitations

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