Advanced Synthesis & Catalysis · 2020 · 93 citations · 404 references
Natural SciencesMedicinal ChemistryPharmacologyDrug DiscoveryOrganic ChemistrySynthetic Medicinal ChemistryHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsOrganic SynthesisHeterocyclic Medicinal ChemistryIsoquinoline ChemistryIsoquinoline SynthesisMedicinal HeterocyclesNitrogen HeterocyclesQuinoline Synthesis
Abstract In the past decades, an enormous number of reports have been dedicated towards the synthesis of nitrogen containing heterocycles. This immense interest have emerged owing to their wide varieties of pharmacological activities. The present review focused on the synthesis of isoquinoline derivatives, a family of N ‐heterocycles showing a broad range of structural diversity, biological and pharmaceutical activities. The progress on their synthetic strategies using versatile approaches are discussed in details. magnified image
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Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C–H Activation
Todd K. Hyster, Livia Knörr, Thomas R. Ward et al. · Science · 2012 · 806 citations · Full text