A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ‐aminobutyric acidergic anticonvulsant - Concepedia

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A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ‐aminobutyric acidergic anticonvulsant

DOI Full Paper Access

13

Citations

36

References

2020

Year

Alistair Jones, Melissa Barker‐Haliski, Andrei Ilie, Murray B. Herd, Sarah Baxendale, Celia J. Holdsworth, John‐Paul Ashton, Marysia Placzek, Bodiabaduge A. P. Jayasekera, Christopher J. A. Cowie,

Abstract

These findings establish a multiorganism approach that can identify compounds with evolutionarily conserved molecular targets and translational potential, and so may be useful in drug discovery for epilepsy and possibly other conditions.

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