A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ‐aminobutyric acidergic anticonvulsant

Alistair Jones, Melissa Barker‐Haliski, Andrei Ilie, Murray B. Herd, Sarah Baxendale, Celia J. Holdsworth, John‐Paul Ashton, Marysia Placzek, Bodiabaduge A. P. Jayasekera, Christopher J. A. Cowie,

Epilepsia · 2020 · 13 citations · 36 references

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Abstract

These findings establish a multiorganism approach that can identify compounds with evolutionarily conserved molecular targets and translational potential, and so may be useful in drug discovery for epilepsy and possibly other conditions.

References

36