Dexmedetomidine alleviates non-ventilation associated lung injury via modulating immunology phenotypes of macrophages

Decreased alveolar oxygen induces lung inflammation

Caveh Madjdpour, Ursula R. Jewell, S. Kneller et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2003 · 197 citations

Veterinary Medicine, Immunology, Pathobiology +17

Dexmedetomidine ameliorates LPS induced acute lung injury via GSK-3β/STAT3-NF-κB signaling pathway in rats

Huayun Zhang, Jichen Sha, Xiujing Feng et al. · International Immunopharmacology · 2019 · 64 citations

Veterinary Medicine, Immunology, Pharmacology +12

Effects of Dexmedetomidine Infusion on Inflammatory Responses and Injury of Lung Tidal Volume Changes during One-Lung Ventilation in Thoracoscopic Surgery: A Randomized Controlled Trial

Chun‐Yu Wu, Yifan Lu, Man‐Ling Wang et al. · Mediators of Inflammation · 2018 · 45 citations · Full text

Medicine, Anesthesiology, Surgery +15

Dexmedetomidine attenuates endoplasmic reticulum stress-induced apoptosis and improves neuronal function after traumatic brain injury in mice

Dongdong Sun, Jianhao Wang, Xilei Liu et al. · Brain Research · 2020 · 45 citations

Life Sciences, Neuroscience, Pharmacology +16

Effects of dexmedetomidine pretreatment on heme oxygenase-1 expression and oxidative stress during one-lung ventilation.

Shenqiang Gao, Yuelan Wang, Jun Zhao et al. · PubMed · 2015 · 41 citations

Medicine, Oncology, Pharmacology +11