RSC Advances · 2020 · 10 citations · 28 references
PharmacyMicrobiologyPharmaceuticsDrug DesignDrug DiscoveryAntibacterial AgentsAntibacterial TherapyAntimicrobial PeptidesConjugation ReactionsPeptide ChemistryPeptide Drug DiscoveryAntibacterial PeptidesAntibacterial PropertiesAntimicrobial Peptide ActivityCationic Antimicrobial PeptidesPeptide ConjugatesPeptide ConjugationPeptide Structure-activity RelationshipsPeptide-drug Conjugates
ATCC 25923 was evaluated, and the results showed that the peptide conjugates exhibited higher antibacterial activity than the original unconjugated peptides. Conjugation of AMPs is a promising strategy for designing and identifying new drugs for treating bacterial infections.
28
Chan Bae Park, Kwan-Su Yi, Katsumi Matsuzaki et al. · Proceedings of the National Academy of Sciences · 2000 · 532 citations