Comparison of single breath hyperpolarized ¹²⁹Xe MRI with dynamic ¹⁹F MRI in cystic fibrosis lung disease

Abstract

In CF subjects, ventilation abnormalities are identified by both ¹⁹ F and HP ¹²⁹ Xe imaging. However, these ventilation abnormalities are not entirely congruent. ¹⁹ F and HP ¹²⁹ Xe imaging provide complementary information that enable differentiation of normally ventilated, slowly ventilated, and non-ventilated regions in the lungs.