Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141<sup>+</sup> dendritic cells to activate naïve and memory NY-ESO-1-specific CD8<sup>+</sup> T cells - Concepedia

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Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141<sup>+</sup> dendritic cells to activate naïve and memory NY-ESO-1-specific CD8<sup>+</sup> T cells

DOI Full Paper Access

37

Citations

41

References

2020

Year

Kelly‐Anne Masterman, Oscar Haigh, Kirsteen M. Tullett, Ingrid Leal Rojas, Carina Walpole, Frances E. Pearson, Jonathan Cebon, Christopher Schmidt, Liam O’Brien, Nikita Rosendahl,

Journal for ImmunoTherapy of Cancer

Abstract

These data advocate human CLEC9A-NY-ESO-1 Ab as an attractive strategy for specific targeting of CD141<sup>+</sup> DCs to enhance tumor immunogenicity in NY-ESO-1-expressing malignancies.

References

	Year	Citations

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