Six-Gene Signature Associated with Immune Cells in the Progression of Atherosclerosis Discovered by Comprehensive Bioinformatics Analyses

Abstract

In this study, we suggested that the progression of atherosclerosis might be related to <i>CD86</i>, <i>C1QB</i>, <i>CD53</i>, <i>C1QC</i>, <i>NCF2</i>, and <i>ITGAM</i> and that it plays a role in regulating immune-competent cells such as T cell CD8 and macrophages M0 and M2. These results will enable studies of the potential genes associated with immune cells in the progression of atherosclerosis, as well as provide insight for discovering new treatments and drugs.