Concepedia

A Comprehensive Phenotypic and Functional Immune Analysis Unravels Circulating Anti–Phospholipase A2 Receptor Antibody Secreting Cells in Membranous Nephropathy Patients

Chiara Cantarelli, Marta Jarque, Andrea Angeletti, Joaquín Manrique, Susan Hartzell, Timothy J. O’Donnell, Elliot Merritt, Uri Laserson, Laura Perin, Chiara Donadei,

Kidney International Reports · 2020 · 47 citations · 43 references

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Abstract

This extensive phenotypic and functional immune characterization shows that autoreactive plasma cells are present in the circulation of MN patients, providing a new therapeutic target and a candidate biomarker of disease activity.

References

43

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