Detection of early cartilage degeneration in the tibiotalar joint using 3 T gagCEST imaging: a feasibility study

Abstract

In this feasibility study, pre-morphological tibiotalar joint cartilage damage was quantitatively assessable on the basis of the optimized 3 T gagCEST imaging protocol that allowed stable quantification gagCEST effect sizes across a wide range of health and disease in clinically feasible acquisition times.