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Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice

Yi Xu, Kun Cao, Bing Guo, Jie Xiang, Yang‐Ting Dong, Xiaolan Qi, Wenfeng Yu, Yan Xiao, Zhi‐Zhong Guan

Aging · 2020 · 22 citations · 26 references

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Abstract

mice, which might help explain the impaired cognition in T2DM.

References

26

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Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity

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Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease

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Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

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