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Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo

Medicinal ChemistryBiochemistryFunctional SelectivityMedicineNatural SciencesMechanism Of ActionMolecular PainPharmacological AgentNeuropharmacologyPharmacotherapyAntinociceptive EffectsPharmacologyPharmaceutical ChemistryDrug DiscoveryDrug-like Properties