Concepedia

Palladium-catalysed C–F alumination of fluorobenzenes: mechanistic diversity and origin of selectivity

Feriel Rekhroukh, Wenyi Chen, Ryan K. Brown, Andrew J. P. White, Mark R. Crimmin

Chemical Science · 2020 · 27 citations · 51 references

DOIFull text

Open access

Concepts

Abstract

. In this instance, the kinetic C-H alumination intermediate could be isolated. Under catalytic conditions this intermediate converts to the thermodynamic C-F alumination product.

References

51

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition‐Metal Complexes

Eric M. Simmons, John F. Hartwig · Angewandte Chemie International Edition · 2012 · 2.1K citations

, , +14

Fluorine in health care: Organofluorine containing blockbuster drugs

David O’Hagan · Journal of Fluorine Chemistry · 2010 · 846 citations

, , +4

C−F and C−H Bond Activation of Fluorobenzenes and Fluoropyridines at Transition Metal Centers: How Fluorine Tips the Scales

Eric Clot, Odile Eisenstein, Naseralla A. Jasim et al. · Accounts of Chemical Research · 2011 · 477 citations

, , +16

Synthesis of Fluorinated Building Blocks by Transition‐Metal‐Mediated Hydrodefluorination Reactions

Moritz F. Kuehnel, Dieter Lentz, Thomas Braun · Angewandte Chemie International Edition · 2013 · 421 citations

, , +9

Ni-Catalyzed Borylation of Aryl Fluorides via C–F Cleavage

Xiang‐Wei Liu, Javier Echavarren, Cayetana Zárate et al. · Journal of the American Chemical Society · 2015 · 239 citations · Full text

, , +4