Concepedia

Synthesis and Biological Evaluation of Novel Dispiro Compounds based on 5-Arylidenehydantoins and Isatins as Inhibitors of p53–MDM2 Protein–Protein Interaction

Anastasia A. Beloglazkina, Alexander A. Barashkin, V. S. Polyakov, German Kotovsky, Sofia Mefedova, Bogdan Zagribelny, Yan A. Ivanenkov, Marina Kalinina, Dmitry A. Skvortsov, N. Zyk,

Chemistry of Heterocyclic Compounds · 2020 · 24 citations · 18 references

DOI

Concepts

References

18

Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations

, , +6

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations

, , +15

The p53-mdm-2 autoregulatory feedback loop.

J. Henri Bayle, David C. Olson, Arnold J. Levine · Genes & Development · 1993 · 1.8K citations · Full text

, , +14

MTT colorimetric assay for testing macrophage cytotoxic activity in vitro

Mario Ferrari, M. C. Fornasiero, Anna Maria Isetta · Journal of Immunological Methods · 1990 · 560 citations

, , +7

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

Jingjie Tang, Jiagui Li, Wei Qi et al. · Cell Metabolism · 2011 · 412 citations · Full text

, , +14