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Synthesis and Biological Evaluation of Novel Dispiro Compounds based on 5-Arylidenehydantoins and Isatins as Inhibitors of p53–MDM2 Protein–Protein Interaction

BiochemistryMedicineRational Drug DesignNovel Dispiro CompoundsBiological EvaluationP53–mdm2 Protein–protein InteractionDrug DevelopmentPharmacologyDrug Discovery