Emerging infectious diseases · 2020 · 14 citations · 13 references
Life SciencesMicrobiologyMolecular BiologyBacteriologyEnvironmental MicrobiologyMedical MicrobiologyAnaerobic BacteriologyBacterial ClassificationBacterial IdentificationBacterial InfectionsBacterial Virulence FactorsPathogen GenomicsAntimicrobial Resistance PatternsContaminant SourcesEnvironmental Contamination SourcesEnvironmental Pathogenic BacteriaVirulence Gene AnalysisVirulence Gene IdentificationWhole-genome Sequence AnalysisWhole-genome Sequencing Analysis
C hromobacterium is a genus of gram-negative, fac- ultative anaerobic bacteria; application of 16S rRNA gene sequencing into bacterial taxonomy is expanding its species (1-5). Most Chromobacterium infections in humans have been caused by C. violaceum (6). Recently, exceptionally rare cases of C. haemolyticum infections have been described (2,4,7-9), but environmental sources of this pathogen have not been well investigated. We describe a case of Chromobacterium-associated pneumonia due to near-drowning and environmental investigation of a river site of the near-drowning. We used whole-genome sequencing (WGS) to identify the Chromobacterium species causing pneumonia associated with near-drowning and investigate molecular features, including antimicrobial resistance, virulence, and genetic relatedness of clinical and environmental isolates of C. haemolyticum.
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