Concepedia

Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension

Junichi Omura, Karima Habbout, Tsukasa Shimauchi, Wenhui Wu, Sandra Breuils‐Bonnet, Ève Tremblay, Sandra Martineau, Valérie Nadeau, Kassandra Gagnon, Florence Mazoyer,

Circulation · 2020 · 164 citations · 59 references

DOIFull text

Open access

Abstract

Our findings identify H19 as a new therapeutic target to impede the development of maladaptive RV remodeling and a promising biomarker of PAH severity and prognosis.

References

59

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

Nazzareno Galiè, Marc Humbert, Jean-Luc Vachiéry et al. · European Heart Journal · 2015 · 6.9K citations · Full text

Survival in Patients with Primary Pulmonary Hypertension

Gilbert E. D’Alonzo, Robyn J. Barst, Stephen M. Ayres et al. · Annals of Internal Medicine · 1991 · 3.5K citations

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

Nazzareno Galiè, Marc Humbert, Jean-Luc Vachiéry et al. · European Respiratory Journal · 2015 · 3.1K citations · Full text

Predicting Survival in Pulmonary Arterial Hypertension

Raymond L. Benza, Dave P. Miller, Mardi Gomberg‐Maitland et al. · Circulation · 2010 · 1.5K citations · Full text

On the C‐statistics for evaluating overall adequacy of risk prediction procedures with censored survival data

Hajime Uno, Tianxi Cai, Michael Pencina et al. · Statistics in Medicine · 2011 · 1.4K citations · Full text