National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

Abstract

A multicenter collection of bacteremic isolates of <i>Escherichia coli</i> (<i>n</i> = 423), <i>Klebsiella pneumoniae</i> (<i>n</i> = 372), <i>Pseudomonas aeruginosa</i> (<i>n</i> = 300), and <i>Acinetobacter baumannii</i> complex (<i>n</i> = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for <i>mcr</i> genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant <i>K. pneumoniae</i> (<i>n</i> = 28) and one (20%) carbapenem-resistant <i>E. coli</i> (<i>n</i> = 5) isolate harbored <i>bla</i>_KPC (<i>n</i> = 17), <i>bla</i>_OXA-48 (<i>n</i> = 2), and <i>bla</i>_VIM (<i>n</i> = 1) genes.