PubMed · 2020 · 12 citations · 20 references
Life SciencesMolecular BiologyOncologyCarcinogenesisGene ExpressionMolecular OncologyCancer BiomarkersCancer TranscriptomicsHormone SignalingSerotonergic SignalingTranscriptomic ProfilingTumor Markers5-Hydroxytryptamine Receptor PharmacologyBreast Cancer Molecular SubtypesCdna SynthesisExpression Level VariationMessenger Rna Biomarker AnalysisSerotonin Receptor Gene ExpressionSerotonin Receptors
The results indicated an increase in the mRNA expression of serotonin receptors (5HTR2A and 5HTR3A) in the tumor tissue compared to the marginal zone, which due to the mitogenic nature of these receptors, is likely to induce more proliferation of cancer cells.
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Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2016 · 16.2K citations · Full text
Serotonin promotes tumor growth in human hepatocellular cancer†
Christopher Soll, Jae Hwi Jang, Marc‐Oliver Riener et al. · Hepatology · 2009 · 216 citations · Full text