Concepedia

[<sup>18</sup>F]CB251 PET/MR imaging probe targeting translocator protein (TSPO) independent of its Polymorphism in a Neuroinflammation Model

Kyungmin Kim, Sung-Hwan Bae, Seok-Yong Lee, Young-Hwa Kim, Juri Na, Chulhee Lee, Min Sun Lee, Guen Bae Ko, Kyeong Yun Kim, Sang‐Hee Lee,

Theranostics · 2020 · 30 citations · 33 references

DOIFull text

Open access

Concepts

Abstract

F]CB251-PET/MRI, tested for evaluating the efficacy of anti-inflammatory agents in preclinical studies, might be an effective method to assess the severity and therapeutic response of neuroinflammation.

References

33

Structural and functional features of central nervous system lymphatic vessels

Antoine Louveau, Igor Smirnov, Timothy Keyes et al. · Nature · 2015 · 4.3K citations

, , +14

Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

William A. Banks, Alicia M. Gray, Michelle A. Erickson et al. · Journal of Neuroinflammation · 2015 · 625 citations · Full text

, , +17

Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands

David R. Owen, Roger N. Gunn, Eugenii A. Rabiner et al. · Journal of Nuclear Medicine · 2010 · 354 citations · Full text

, , +13

Comparison of [11C]-(R)-PK 11195 and [11C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker

William Charles Kreisl, Masahiro Fujita, Yota Fujimura et al. · NeuroImage · 2009 · 274 citations · Full text

, , +15

Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-(1-methylpropyl)-3 isoquinolinecarboxamide

G. Le Fur, F. Guilloux, Pierre Rufat et al. · Life Sciences · 1983 · 227 citations

, , +6