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Publication | Open Access

Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma

DOIFull Paper Access

366

Citations

29

References

2020

Year

Carlos A. Ramos, Natalie S. Grover, Anne Beaven, Premal Lulla, Meng-Fen Wu, Anastasia Ivanova, Tao Wang, Thomas C. Shea, Cliona M. Rooney, Christopher Dittus,
Journal of Clinical Oncology

Abstract

Heavily pretreated patients with relapsed or refractory HL who received fludarabine-based lymphodepletion followed by CD30.CAR-Ts had a high rate of durable responses with an excellent safety profile, highlighting the feasibility of extending CAR-T cell therapies beyond canonical B-cell malignancies.

References

YearCitations

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