Theranostics · 2020 · 287 citations · 39 references
Veterinary MedicineMolecular BiologyPathobiologyEpigeneticsGene ExpressionInflammationEndothelial ActivationEndothelial DysfunctionInflammatory MediatorsInflammatory SignalingAtherosclerosis Molecular MechanismsEndothelial InflammationForkhead Box O SignalingForkhead Box Protein O1 RegulationForkhead Box ProteinsInflammation In Cardiovascular DiseaseN6-methyladenosine RegulationRna Immunoprecipitation
A modification and inducing endothelial cell inflammatory response as well as atherosclerotic plaque formation. Decreased expression of METTL14 can inhibit endothelial inflammation and atherosclerosis development. Therefore, METTL14 may serve as a potential target for the clinical treatment of atherosclerosis.
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Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
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