Antibacterial and antibiofilm properties of ZnO nanoparticles synthesis using gum arabic as a potential new generation antibacterial agent

Abstract

This study aimed to investigate the antibacterial properties of gum arabic-ZnO nanoparticles. The antibacterial and antibiofilm activities of gum arabic-ZnO nanoparticles were evaluated against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) value of gum arabic-ZnO nanoparticles for S. aureus and E. coli was 31.25 μg/mL, 62.5 μg/mL and 62.5 μg /mL, 125 µg/mL respectively. At higher concentrations above 500 μg/mL, the percentage of toxicity to biofilm was observed more than 50% for both S. aureus and E. coli. Therefore gum arabic-ZnO nanoparticles are suggested as a natural new generation antibacterial agent.