Oxalate Nephropathy Caused by Excessive Vitamin C Administration in 2 Patients With COVID-19

Abstract

Kidney dysfunction is frequently reported in patients with coronavirus disease 2019 (COVID-19). A recent large cohort study described an incidence of acute kidney injury (AKI) of 36% in patients who were hospitalized with COVID-19; AKI (often mild) was temporally linked with respiratory failure and associated with a poor prognosis.1 Many factors may be at play in determining kidney dysfunction in patients with COVID-19 who are critically ill; moreover, human kidneys have been reported as potential targets for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.