THE STRUCTURE OF RYANODINE. I

Abstract

Ryanodine consumes one mole of periodic acid and gives oxoryanodine C 25 H 33 O 9 N. Splitting off water from ryanodine gives anhydroryanodine C 25 H 33 O 8 N. The analyses of these two derivatives are therefore in agreement with the formula for ryanodine C 25 H 35 O 9 N. Alkaline hydrolysis of ryanodine gives pyrrole-α-carboxylic acid and an alcohol C 20 H 32 O 8 . This alcohol splits off water to give a compound C 20 H 30 O 7 . Alkaline hydrolysis of oxoryanodine consumes three moles of alkali and gives a mixture of low molecular acidic products. Alkaline fusion of oxoryanodine gives a neutral aromatic nitrogen-free crystalline substance.