A fluorescence-readout method for miRNA-155 detection with double-hairpin molecular beacon based on quadruplex DNA structure

Circulating microRNAs as stable blood-based markers for cancer detection

Patrick S. Mitchell, Rachael K. Parkin, Evan M. Kroh et al. · Proceedings of the National Academy of Sciences · 2008 · 8K citations · Full text

Medicine, Molecular Biology, Oncology +17

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

Brenda J. Reinhart, Frank J. Slack, Michael Basson et al. · Nature · 2000 · 5K citations

Life Sciences, Molecular Biology, Molecular Genetics +13

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

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Molecular Beacons: Probes that Fluoresce upon Hybridization

Sanjay Tyagi, Fred Russell Kramer · Nature Biotechnology · 1996 · 4.2K citations

Natural Sciences, Biology, Molecular Biology +9

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

Dipankar Sen, Walter Gilbert · Nature · 1988 · 1.8K citations

Life Sciences, Genetics, Molecular Biology +14