Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance

Abstract

In the era of increasing macrolide- and quinolone-resistant <i>Mycoplasma genitalium</i> (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%-85%), and minocycline cured 71% (95% CI, 54%-85%) of cases. These data provide useful estimates to inform clinical practice.