Pediatric Blood & Cancer · 2020 · 33 citations · 16 references
MedicineOncologyPediatricsHepatologyPediatric OncologyRadionuclide TherapyHepatobiliary CancerHepatobiliary SurgeryLiver CancerLiver DiseasePediatric HepatologyPediatric Liver DiseaseCurative InterventionHepatic TumorsHepatoblastoma ResectionHepatoblastoma SurgeryLiver NeoplasmsLiver Tumor TherapyTransarterial RadioembolizationYttrium-90 Radioembolization
Primary malignant liver tumors are rare but all require surgical resection as part of therapy with curative intent. A minority of patients have resectable tumors at diagnosis. Chemotherapy has a therapeutic role in hepatoblastoma but only one-third of patients have resectable disease at diagnosis. Two children with hepatoblastoma and suboptimal responses to initial chemotherapy received therapy with transarterial radioembolization utilizing yttrium-90 (TARE-Y90) and had significant response leading to resection and remission. The role of TARE-Y90 needs to be studied further to define its use in primary pediatric liver neoplasms.
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New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
E. Eisenhauer, P. Therasse, Jan Bogaerts et al. · European Journal of Cancer · 2008 · 29.5K citations