<i>APOE ϵ</i> 4 modifies the relationship between infectious burden and poor cognition

Abstract

OBJECTIVE: is an effect modifier of the association between infectious burden (IB) and poor cognition in a multiethnic cohort, the Northern Manhattan Study. METHODS: and IBI. RESULTS: 4 carriers (β = 0.27, 95% CI -0.09 to 0.64). CONCLUSIONS: 4 allele on the relationship of infection, and particularly viral infection, to cognitive processing speed warrants further investigation.