High expression of GNB4 predicts poor prognosis in patients with Helicobacter pylori-positive advanced gastric cancer

Abstract

This study demonstrates that high expression of GNB4 is significantly associated with pathological stage of AGC patients with <i>H. pylori</i> infection. GNB4 expression independently predicts the 5-year OS of <i>H. pylori</i>-positive AGC patients undergoing radical gastrectomy and adjuvant chemotherapy.