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Impaired Th1 Response Is Associated With Therapeutic Failure in Patients With Cutaneous Leishmaniasis Caused by<i>Leishmania braziliensis</i>

DOIFull Paper Access

14

Citations

46

References

2020

Year

Augusto M. Carvalho, Luiz Henrique Guimarães, Rúbia Costa, Maíra Garcia Saldanha, Iana Prates, Lucas P. Carvalho, Sérgio Arruda, Edgar M. Carvalho
The Journal of Infectious Diseases

Abstract

In LST-negative patients, impaired Th1 response is associated with therapeutic failure. Increased frequency of CD8+ T cells and high production of inflammatory cytokines, granzyme B, and MMP-9 contributes to immunopathology.

References

YearCitations

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