Publication | Open Access
Drug-induced Liver Injury in a Patient With Coronavirus Disease 2019: Potential Interaction of Remdesivir With P-Glycoprotein Inhibitors
71
Citations
5
References
2020
Year
Coronavirus Disease 2019HepatologyMedicineLiver PhysiologyAntiviral Drug DevelopmentAntiviral TherapyVirologyRemdesivir TherapyHepatotoxicityPharmacotherapyAcute Liver FailureP-gp InhibitorsAntiviral DrugPharmacologyDrug-induced Liver InjuryProbable InteractionP-glycoprotein Inhibitors
We report a case of a man with COVID-19 who developed acute hepatotoxicity related to remdesivir with probable interaction of P-glycoprotein (P-gp) inhibitors. Until further details on this interaction become available, we recommend physicians to be cautious with the prescription of P-gp inhibitors in patients receiving remdesivir therapy.
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