Concepedia

An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9.

Orly Goldstein, Jason G. Mezey, Adam R. Boyko, Chuan Gao, Wei Wang, Carlos D. Bustamante, Lynne J. Anguish, Julie Ann Jordan, Susan E. Pearce-Kelling, Gregory M. Acland

PubMed · 2010 · 46 citations · 29 references

Abstract

Identification of this ADAM9 deletion in crd3-affected dogs establishes this canine disease as orthologous to CORD9 in humans, and offers opportunities for further characterization of the disease process, and potential for genetic therapeutic intervention.

References

29

Genome sequence, comparative analysis and haplotype structure of the domestic dog

Nature · 2005 · 2.6K citations · Full text

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Gene therapy restores vision in a canine model of childhood blindness

Gregory M. Acland, Jharna Ray, Qí Zhāng et al. · Nature Genetics · 2001 · 1.2K citations

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Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication

Bridgett M. vonHoldt, John P. Pollinger, Kirk E. Lohmueller et al. · Nature · 2010 · 803 citations · Full text

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Efficient mapping of mendelian traits in dogs through genome-wide association

Elinor K. Karlsson, Izabella Baranowska, Claire M. Wade et al. · Nature Genetics · 2007 · 546 citations

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A metalloprotease-disintegrin, MDC9/meltrin-gamma /ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor

Yasushi Izumi · The EMBO Journal · 1998 · 516 citations · Full text

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