Concepedia

Fibroblast Activation Protein (FAP) specific PET for advanced target volume delineation in glioblastoma

Paul Windisch, Manuel Röhrich, Sebastian Regnery, Eric Tonndorf‐Martini, Thomas Held, Kristin Lang, Denise Bernhardt, Stefan Rieken, Frederik L. Giesel, Uwe Haberkorn,

Radiotherapy and Oncology · 2020 · 63 citations · 19 references

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Abstract

Fibroblast Activation Protein (FAP)-specific Positron Emission Tomography (PET) has shown promising results in various cancers. This pilot study compares FAP-specific PET to MRI for treatment planning in 13 Glioblastoma patients. The resulting incongruent volumes could provide additional information for radiotherapy or biopsy planning.

References

19

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Clemens Kratochwil, Paul Flechsig, Thomas Lindner et al. · Journal of Nuclear Medicine · 2019 · 1.4K citations · Full text

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Development of Quinoline-Based Theranostic Ligands for the Targeting of Fibroblast Activation Protein

Thomas Lindner, Anastasia Loktev, Annette Altmann et al. · Journal of Nuclear Medicine · 2018 · 920 citations · Full text

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A Tumor-Imaging Method Targeting Cancer-Associated Fibroblasts

Anastasia Loktev, Thomas Lindner, Walter Mier et al. · Journal of Nuclear Medicine · 2018 · 770 citations · Full text

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High-grade glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Roger Stupp, M. Brada, Martin J. van den Bent et al. · Annals of Oncology · 2014 · 763 citations · Full text

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<sup>68</sup>Ga-FAPI PET/CT: Biodistribution and Preliminary Dosimetry Estimate of 2 DOTA-Containing FAP-Targeting Agents in Patients with Various Cancers

Frederik L. Giesel, Clemens Kratochwil, Thomas Lindner et al. · Journal of Nuclear Medicine · 2018 · 722 citations · Full text

, , +17