Concepedia

Magnesium sulfate ameliorates sepsis-induced diaphragm dysfunction in rats via inhibiting HMGB1/TLR4/NF-κB pathway

Jihong Jiang, Qi Chen, Xia Chen, Jinbao Li, Shitong Li, Bin Yang

Neuroreport · 2020 · 23 citations · 44 references

DOIFull text

Open access

Abstract

MgSO4 protects against sepsis-induced diaphragm dysfunction. This may be associated with its anti-inflammatory effect on HMGB1/TLR4/NF-κB signal pathway.

References

44

HMGB1 SIGNALS THROUGH TOLL-LIKE RECEPTOR (TLR) 4 AND TLR2

Man Yu, Haichao Wang, Aihao Ding et al. · Shock · 2006 · 816 citations

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

Tobias Bald, Thomas Quast, Jennifer Landsberg et al. · Nature · 2014 · 610 citations

, , +4

Diaphragm Dysfunction on Admission to the Intensive Care Unit. Prevalence, Risk Factors, and Prognostic Impact—A Prospective Study

Alexandre Demoule, Boris Jung, Hélène Prodanovic et al. · American Journal of Respiratory and Critical Care Medicine · 2013 · 448 citations

Diaphragmatic dysfunction in patients with ICU-acquired weakness and its impact on extubation failure

Boris Jung, Pierre-Henri Moury, Martin Mahul et al. · Intensive Care Medicine · 2015 · 331 citations · Full text

, , +2

Increased duration of mechanical ventilation is associated with decreased diaphragmatic force: a prospective observational study

Greet Hermans, Anouk Agten, Dries Testelmans et al. · Critical Care · 2010 · 267 citations · Full text