Peroxy‐Benzoic Acid Mediated Domino C[sp ² ] Hydroxylation /Annulation of Enaminones for the Synthesis of 3‐Hydroxy Chromones

Abstract

Abstract An efficient, facile, and clean synthesis of various 3‐hydroxy‐chromones (3‐hydroxy‐4H‐chromene‐4‐ones) via enamino ketone followed by cyclization using m‐chloroperbenzoic acid (MCPBA) has been described. The significant features of this method include simple method, high purity and excellent regio‐selectivity of the products. This is the first report for the two step one pot synthesis of 3‐hydroxyl chromone using MCPBA.