Putative Phospholipase B-Like 2 is Not Responsible for Polysorbate Degradation in Monoclonal Antibody Drug Products

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

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Polysorbates 20 and 80 Degradation by Group XV Lysosomal Phospholipase A 2 Isomer X1 in Monoclonal Antibody Formulations

Troii Hall, Stephanie Sandefur, Christopher C. Frye et al. · Journal of Pharmaceutical Sciences · 2016 · 172 citations

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Residual Host Cell Protein Promotes Polysorbate 20 Degradation in a Sulfatase Drug Product Leading to Free Fatty Acid Particles

Nitin Dixit, Nazila Salamat‐Miller, Paul A. Salinas et al. · Journal of Pharmaceutical Sciences · 2016 · 165 citations

Life Sciences, Biochemistry, Molecular Biology +10

Ester Hydrolysis of Polysorbate 80 in mAb Drug Product: Evidence in Support of the Hypothesized Risk After the Observation of Visible Particulate in mAb Formulations

Steven R. LaBrenz · Journal of Pharmaceutical Sciences · 2014 · 152 citations

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