Natural product diversity from the endophytic fungi of the genus<i>Aspergillus</i>

Abstract

The endophytic fungus <i>Aspergillus</i> is considered as an enormous source of chemical leads with promising biological activities. Different <i>Aspergillus</i> species have proved their ability to produce plenty of secondary metabolites including butenolides, alkaloids, terpenoids, cytochalasins, phenalenones, ρ-terphenyls, xanthones, sterols, diphenyl ether and anthraquinone derivatives with diverse biological activities, such as anti-cancer, antifungal, anti-bacterial, anti-viral, anti-inflammatory, antitrypanosomal and antileishmanial activities. From January 2015 until December 2019, three hundred and sixty-one secondary metabolites were reported from different endophytic <i>Aspergillus</i> species. This review discusses the isolated secondary metabolites from different endophytic <i>Aspergillus</i> species reported from January 2015 to December 2019 along with their reported biological activities and structural aspects whenever applicable.