Alpha-pinene exerts neuroprotective effects via anti-inflammatory and anti-apoptotic mechanisms in a rat model of focal cerebral ischemia-reperfusion

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.5K citations · Full text

Medicine, Neuroscience, Surgery +17

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

Kennedy R. Lees, Erich Bluhmki, Rüdiger von Kummer et al. · The Lancet · 2010 · 2.2K citations

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A Semiautomated Method for Measuring Brain Infarct Volume

Raymond A. Swanson, Matthew T. Morton, George Tsao-Wu et al. · Journal of Cerebral Blood Flow & Metabolism · 1990 · 1.7K citations

Medicine, Neurology, Neuroscience +16

Microglia and ischemic stroke: a double-edged sword.

Anita Patel, Rodney M. Ritzel, Louise D. McCullough et al. · PubMed · 2013 · 333 citations

Life Sciences, Neurobiology, Neuroscience +17

Alpha-Pinene Exhibits Anti-Inflammatory Activity Through the Suppression of MAPKs and the NF-κB Pathway in Mouse Peritoneal Macrophages

Dae-Seung Kim, Hyun-Ja Lee, Yong‐Deok Jeon et al. · The American Journal of Chinese Medicine · 2015 · 266 citations

Life Sciences, Immunology, Pharmacology +17