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Preoperative denosumab treatment with curettage may be a risk factor for recurrence of giant cell tumor of bone

Kei Sano, Yoshiyuki Suehara, Taketo Okubo, Keita Sasa, Taisei Kurihara, Keisuke Akaike, Daisuke Kubota, Tomoaki Torigoe, Nobuhiko Hasegawa, Midori Ishii,

Journal of orthopaedic surgery · 2020 · 24 citations · 24 references

DOIFull text

Open access

Abstract

Our findings revealed the use of denosumab in GCTB, prior to curettage, to possibly increase the risk of local recurrence. Together with previous reports, our finding might provide information for beneficial treatment of GCTB.

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